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KMID : 0382620000200020005
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Hanyang Journal of Medicine
2000 Volume.20 No. 2 p.5 ~ p.8
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Bone Marrow Transplantation in Malignant Lymphoma
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Abstract
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Patients with malignant lymphoma can be induced into a complete remission with chemotherapy. But stem cell transplantation has become widespread in the treatment of patients with refractory or relapsed NHL. High-dose therapy and autologous BMT are superior to conventional therapy in relapsed patients while the majority of patients undergoing BMT have intermediate and high-grade NHL.
High-dose chemotherapy with autologous BMT has been widely employed as cytoreductive treatment for low-grade lymphoma.
High-dose chemotherapy and autologous BMT has resulted in improved cure rates for patients with recurrent, chemotherapy-sensitive, large cell lymphoma compared to continuing salvage chemotherapy alone. The use of high-dose therapy by autologous hematopoietic cell transplantation has become accepted for patients with relapsed and refractory Hodgkin´s disease.
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